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Transmissibility and clinical significance of Mycobacterium abscessus in patients with cy
     
 
Author(s) : Tortoli E, Cariani L, Di Serio C, Niemann S
Address : Istituto Scientifico San Raffaele, Milano; Università Vita-Salute San Raffaele, Milano, Italy.
Multiple Institutions in collaboration
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Background. M. abscessus (MA) is a species frequently isolated from cystic fibrosis (CF) patients. Three Subspecies (subsp.) of MA exist and their identification is crucial for epidemiology and optimal patient’s management. Although the environment is considered the source of MA infections, its transmission between CF patients has been hypothesized. 

Objectives. We aimed to investigate a large collection of MA isolates obtained from CF patients to increase present knowledge about the prevalence of the 3 subsp., their antimicrobial susceptibility, the presence of MA genotypes characterized by increased virulence and responsible for severe clinical manifestations, the transmissibility between patients of the infection. 

 
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